Prof. John Aplin University of Manchester, UK
I was a Chemistry undergraduate in Oxford and got interested in surfaces. My PhD with Laurie Hall at UBC in Vancouver was in Biophysical Chemistry, and involved studying molecular motion in complex biological environments. In one experiment we showed how long a spacer is needed to optimise ligand availability at the surface of an affinity column. We talked a lot to pathologists and I belatedly realised there might have been a niche for me in medicine after all. Later I became a postdoc with MRC at NIMR, Mill Hill, London where I worked with Colin Hughes on cell adhesion to ECM. Then I moved to a lectureship in the Faculty of Medicine in Manchester where I have been ever since, except for a sabbatical stay in Stan Glasser’s lab at Baylor. I learned some developmental biology from a postdoc, Steve Campbell, and Stan taught me a lot about embryo implantation and decidualisation. The lab is situated in the Maternal and Fetal Health Centre in the newly integrated Faculty of Biology, Medicine and Health, where we enjoy an excellent interface with both Obstetrics and Fetal Medicine and Reproductive Medicine. In addition to implantation we also work on placental development.
Prof. Kimberly Topp, San Fransisco, USA
Kimberly Topp, PhD, PT, FAAA, FAS (Hon) is Professor and Chair of the Department of Physical Therapy and Rehabilitation Science in the School of Medicine at the University of California, San Francisco, and holds a joint appointment in the Department of Anatomy. Dr. Topp earned her BS in Physical Therapy from Northern Arizona University in 1981 and her PhD in Anatomy and Cell Biology from University of California, Davis in 1990. She completed postdoctoral study in Neurobiology at UCSF and joined the faculty in 1993.
As the UCSF Director of the UCSF/SFSU Graduate Program in Physical Therapy, Dr. Topp oversees the entry-level DPT Program. She also leads the UCSF PhD Program in Rehabilitation Science, the Orthopedic Physical Therapy Residency Program and the Outpatient Physical Therapy Faculty Practices. In the Department of Anatomy, Dr. Topp directs the anatomy curricula for the School of Medicine and the Physical Therapy Program. She is a member of the UCSF Academy of Medical Educators, and has held leadership positions within the university and nationally. Dr. Topp is a Fellow and President (2015-2017) of the American Association of Anatomists.
Dr. Topp’s research interests are in structure-function relationships of peripheral nerve. She has studied the axonal cytoskeletal framework, directional axonal transport, and biomechanical properties of normal and injured nerve in animal models and humans. She is currently studying patients with cancer to phenotypically characterize chemotherapy-induced neuropathy and to identify the populations of cancer survivors who are most at risk for these problematic symptoms.
Prof. Calvin Coffey University Of Limerick, Ireland ;
Professor J Calvin Coffey is the Foundation Chair of Surgery at the Graduate Entry Medical School, University of Limerick and a consultant general and colorectal surgeon at the University Hospital Limerick Group, Limerick. He qualified with a first class honours B.Sc. in Anatomy in 1995, under the supervision of Professor Kieran McDermott, in University College Cork. He qualified in Medicine in 1998 from University College Cork. He obtained a PhD in Surgery in 2006 and completed surgical training in 2010 at the Cleveland Clinic, Ohio, USA. He took up his current post in 2010 and oversaw the implementation of a surgical curriculum as part of the medical degree at GEMS, in UL.
His primary clinical interests are open, minimally invasive and robotic intestinal surgery. He has performed several thousand intestinal resections. He pioneered robotic intestinal surgery in Ireland and his group have received numerous clinical awards including the Healthcare Development Initiative/ Large Teaching Hospital award at the Irish Healthcare Centre Awards, 2017, in recognition of development of robotic intestinal surgery in Ireland. He was invited to present the Distinguished Alumnus Lecture at the Cleveland clinic in 2012. He was awarded the prestigious James the IV International Surgical Fellowship and has been the recipient of numerous named national and international lectures. These include the Millin Lecture, The Sir Thomas Myles Lecture, and more recently the Robert Smith Lecture at the Annual Congress of The Association of Surgeons of Great Britain and Ireland.
His primary research interests relate to the emerging field of mesenteric science. His research group has published several hundred research papers, and been awarded numerous national and international awards including the William O Keefe Prize, The Freyer Prize, The ASGBI Best Paper Prize. He is chief author of the book entitled Mesenteric Principles of Gastrointestinal Surgery: Basic and applied Sciences, and Editor in Chief of the recently established journal “Mesentery and Peritoneum.” He has published in Nature Reviews, The Lancet Gastroenterology and Hepatology on the importance of anatomy in standardising intestinal surgery. His article, “The Mesentery; structure, function and role in disease” reached an Altmetric score of 2020. He has developed numerous novel surgical techniques, based on anatomy, in the surgical management of acquired and congenital abnormalities of the intestine and mesentery.
Prof. Margaret McNulty Louisina State, USA ;
Dr. McNulty’s research area is primarily orthopaedics, specifically focusing on bone and joint pathology, using animal models of human disease. Translational research hinges on use of animal models of human disease, and in many fields (e.g. orthopaedics), the anatomical modifications found in the various quadrupedal species used in these studies directly influence results obtained and how they are translatable to humans. Thusly, knowledge of and investigation into comparative anatomy, including how it relates to human anatomy, is critical to advancing translational research. Specific recent work in the McNulty laboratory has identified novel anatomical characteristics within the murine tarsus that had been previously identified as pathologic, but in fact appears to be normal anatomy specific to the U.S. inbred strains of mice. This work is influencing other studies within the McNulty laboratory that are evaluating bone and joint disease, including murine models of chikungunya virus infection, which is a known arthritogenic virus that is currently responsible for a large outbreak within the Americas.
Dr. Susan Anderson University of Nottingham, England ;
Dr Anderson completed her PhD at the University of Notttingham in 2001 and has worked there since; initially as Director of the advanced microscopy facility and then as academic lead for Pathology before becoming the Director of Undergraduate Studies in the School of Medicine. She is also the Head of Education and Outreach for the Royal Microscopical Society, leading a successful schools science outreach programme and professional Dipoma qualification as well as leading the public engagement activities of the Society. Susan is also the deputy director of the BBSRC Doctoral Training Programme at the University of Nottingham. She has research interests in bone metabolism and Medical Education. She has introduced the use of virtual microscopy and pathology to over 1000 students at the University of Nottingham and is currently writing a textbook on Essential Clinical Histology.
Prof. John Milton Lucocq. University of St. Andrews, Scotland;
John Lucocq has been at the University of St Andrews since 2011. For 35 years he has worked in the area of structural cell biology and has led a membrane traffic cell biology group and a number of EM facilities. His biological interests are in the compartmentation of protein kinase and lipid signaling, mitotic control of membrane traffic pathways as well as the evolution of mitochondrial and host parasite interactions. He identified the mitosome ultrastructurally. Recently he has focused on disease and drug targets in the endosome. His microscopical interests focus on 3D quantification from sections (including stereology and other morphomics methods), developing methods for quantifying immuno-EM signals, the application of deep learning strategies for organelle recognition, and developing new methods for quantifying synthetic and naturally occurring nanoparticles.
Morphological analysis is fundamental to understanding cell and tissue function. Cells and organelles comprise rich arrays of 3D data that can be mined across the imaging scales of light and electron microscopy to yield precise and bias-free measurements. Recently I introduced the terms morphome for the spatial distribution of matter in a biological object, and morphomics for methods that systematically or quantitatively assesses a 3D data set. At the nanometer scale morphomics can yield petabytes of data and a big question is how to estimate high quality data easily and rapidly. I will discuss solutions to this “large data” problem and strategies for removing or negotiating technological roadblocks to higher-throughput. I will also address issues such as automated recognition, the integration of EM data with readouts from other imaging modes and how the morphome integrates into the ‘omics framework.
Dr. Eleanor Coffey, University of Turku, Finland;
Eleanor Coffey graduated from Trinity College Dublin in 1990 and received her PhD in 1994 from the University of Dundee where she studied molecular mechanisms of synaptic transmission. She was awarded a Wellcome Trust Traveling Fellowship and thereafter an Academy of Finland Postdoctoral Fellowship to work on protein kinase function in brain. She is currently Research Director at Turku Centre for Biotechnology where she has led a group since 2000 working on protein kinase function in brain. She also heads the Cell Imaging Core at the Center which consists of an independent research and service unit of the two universities in Turku that hosts state-of-the-art national infrastructures for imaging, next generation sequencing and mass spectrometry. Her lab investigates the molecular mechanisms of brain function in disease with a focus on the protein kinases JNK and LRRK2. They are particularly interested in the function of JNK in dendrite and spine architecture regulation as well as neurogenesis. Her group has helped characterise JNK function in brain, identifying critical roles in radial migration, dendrite architecture regulation and more recently in the control of adult hippocampal neurogenesis. This work contributes new understanding of JNK dysfunction underlying psychiatric disorders. Methods used include imaging, optogenetic tools, proteomics, biochemistry and behavioural studies.
Dr. Brian Metscher, University of Vienna, Austria;
Following bachelor’s work in applied physics at Caltech and a first career as a research engineer at NASA/JPL, Dr. Metscher completed his Ph.D. in the then-new interdiscipline of evo-devo at the University of California, Irvine. He did postdoctoral research on the development and evolution of appendages and teeth at The Natural History Museum (London) and Penn State University, and then served five years as an Assistant Professor in southern Indiana. During the summers he carried out research at Yale University and finally came to the University of Vienna in 2006, to set up the imaging lab in the Theoretical Biology Department. Dr. Metscher helped to establish x-ray microtomography as an essential method for imaging ex vivo biological samples, especially embryos and invertebrates. His lab is developing new and refined sample preparation and imaging methods, with applications including molecular imaging and imaging of specific cells types
Prof. Martin Leahy, National University of Ireland Galway, Ireland;
Martin Leahy completed a DPhil at the University of Oxford and he and a colleague established Oxford Optronix Ltd., where he was Director of R&D. From 1995 he had various research and teaching posts at the University of Oxford. He then joined the Stokes Research Institute where he conducted industry led R&D and later the Physics Department at the University of Limerick where led research groups in energy and biophotonics and lectured in physics. He has secured more than €7M in external R&D funding since 2003. He is an adjunct professor at the Royal College of Surgeons, Fellow of the Institute of Physics, Fellow of the Royal Academy of Medicine in Ireland and Fellow of SPIE. He is a co-chair, executive organizing committee member, panel moderator for SPIE Photonics West BiOS in San Francisco and Editorial Board member of the Journal of Biomedical Optics. and host of the BioPIC European Bioimaging conference. Prof Leahy was founding MD of Limerick West Windfarms Ltd. and Millstream Energy and PI on the research projects that spun out Biomass Heating Solutions Ltd. and Wheelsbridge AB. Since his return to full-time academia, he has played a leading role in graduate biophotonics education through NBIP, UL and the Biophotonics and Imaging Graduate Summer School. Since 2010 he has delivered more than 20 international invited lectures and published more than 40 ISI journal articles. He is currently Chair of Applied Physics at NUI Galway and was elected to Council of the Royal Microscopical Society in 2015.
Dr. Xiangmin Xu, University of California, Irvine, USA;
I have a strong background in biology, engineering and medicine that I apply to answering fundamental questions in neuroanatomical and neurophysiological sciences. My interests focus on neural circuit organization and function, in relation to the neurobiology of visual perception, learning and memory. We use a cutting-edging, multidisciplinary approach that combines electrophysiology, photostimulation and optical imaging, molecular genetics and viral tracing. Understanding how neural circuits give rise to perception, cognition, and behavior is central to understanding how the brain works. This is also important for understanding neurological and neuropsychiatric disorders. My research achievements are reflected by our publications in the highest impact journals, and my receipt of prestigious awards as an independent investigator. I have active collaborations with other successful investigators located in major research institutions in southern California and other regions. Our research program is supported by NIH grants and private foundation funds.
Prof. Laoise McNamara, National University of Ireland Galway, Ireland;
Professor Laoise McNamara is a Personal Professor of Biomedical Engineering in the College of Engineering and Informatics at the National University of Ireland, Galway. She established the Mechanobiology and Medical Device Research team at NUI Galway in 2009, which is currently comprised of eight PhD students, four Postdoctoral fellows and a research assistant. Most notably she was awarded the ERC Starting Independent Researcher Award in 2011 for a 5 year funded program of research entitled “Frontier research in bone mechanobiology during normal physiology, disease and for tissue regeneration”. Through the ERC funding Dr. McNamara’s research group are using multidisciplinary approaches to derive an understanding of bone mechanobiology and how this process contributes to bone development, physiology and the aetiology of Osteoporosis. She was recently awarded a Science Foundation Ireland Investigators Grant to pursue research emanating from the findings from the ERC project specifically focused on identifying new mechanobiology-based therapeutic approaches for treatment of osteoporosis. She has also been awarded various other Health Research Board, SFI and Irish Research Council funding. Dr. McNamara’s research group have been awarded numerous presentation prizes and travel awards (American Society for Mechanical Engineering, American Society for Bone and Mineral Research, Orthopaedic Research Society, European Society for Biomechanics, MIMICS Innovation Award, Engineers Ireland, Bioengineering in Ireland, Fulbright, NUI and SFI travelling scholarships). She has interdisciplinary research collaborations with researchers at Georgia Tech, Notre Dame University, City College of New York, Worcester Polytechnic Institute, Tampere University of Technology, INSERM Nantes and the University of Southampton. She collaborates with Stryker, Boston Scientific and Medtronic applying her expertise in computational and experimental biomechanics to the pre-clinical assessment of surgical and minimally invasive medical devices.
Prof. Emiliano Bruner the National Research Center for Human Evolution, Burgos, Spain,
Emiliano Bruner is PhD in Animal Biology and Research Group Leader in Paleoneurology at the National Research Center for Human Evolution in Burgos (Spain). He is Adjoint Professor in Paleoneurology at the Center for Cognitive Archaeology, University of Colorado (USA). He applies digital anatomy and computed morphometrics in evolutionary neuroanatomy and functional craniology. His main researches concern parietal lobe evolution, craniovascular biology, and evolutionary anthropology.
Personal webpage: https://paleoneurology.wordpress.com
Dr. Michael Hortsch, University of Michigan, USA,
MICHAEL HORTSCH, Ph.D., is an associate professor in the Departments of Cell and Developmental Biology and of Learning Health Sciences at the University of Michigan Medical School in Ann Arbor, Michigan. Since 1991 he has taught medical and dental histology at the University of Michigan. He is a recipient of the 2012 Kaiser Permanente Award for Excellence in Pre-Clinical Teaching from the University of Michigan Medical School and the 2013 University of Michigan Provost’s Teaching Innovation Prize. He is interested in the development of novel electronic teaching tools and how these new resources impact students’ learning. Under the SecondLook™ label he has published a series of mobile smartphone and computer tablet applications for students to review different topics of the anatomical sciences. The results of his medical education research have been published in several leading journals in the field, among others, the FASEB Journal, Anat. Sci. Educ., Medical Teacher, Med. Sci. Educ.
Prof. Sabine Koelle, University College Dublin, Ireland.
Sabine Koelle is Professor of Anatomy and Developmental Biology at the University College Dublin, School of Medicine and Medical Sciences since 2013. She graduated in Veterinary Medicine at the University of Munich, where she also did studies in medicine and dentistry. She received her habilitation in the Institute of Veterinary Anatomy, Histology and Embryology of the University of Munich, Germany. In 2004 she was appointed as associate professor in the Institute of Anatomy, Histology and Embryology in the University of Giessen. In 2009 she was appointed as Full Professor and Head of the Department of Anatomy, Histology and Embryology at the University of Vienna, Austria.
Professor Koelle`s research is focused on reproductive medicine, especially on establishing new technologies for in vivo imaging of the male and female genital tract and improving the results of assisted reproduction. Recent research projects include the mechanisms of gameto-maternal interaction, embryo-maternal communication and early embryogenesis in humans
Prof. Kurt Albertine, Utah, USA
Prof. Kenneth Bo Foreman , Utah, USA
K. Bo Foreman, PhD, PT received his B.S. in Physical Therapy from the University of Utah, College of Health in 1994 and his Ph.D. in Anatomy from the University of Utah, School of Medicine in 2005. Following graduation, Dr. Foreman joined the faculty in the Department of Physical Therapy and Athletic Training at the University of Utah in 2005 and currently holds the position of Associate Professor. In addition, he is the Director of the Motion Analysis Core Facility at the University of Utah, Director of the Gait Lab at the Veterans Administration Medical Center in Salt Lake City, Utah, and serves as an Associate Editor for The Anatomical Record.
His research interests are in the area biomechanics, specifically the investigation of the kinetic and kinematic changes that result from clinical interventions and/or disease progression. Current projects involve the investigation of using virtual reality as a rehabilitation tool, using biomechanics as a mode of biofeedback to improve gait, and using biomechanically modeling to improve clinical decision-making.
His primary teaching responsibilities are gross anatomy and neuroanatomy in the Department of Physical Therapy and Athletic training. In addition, Dr. Foreman provides courses for the College of Engineering and various clinical programs.